Gating of Mechanosensitive Piezo and Swell Ion Channels in Droplet Lipid Bilayers

Pittsburgh Center for Pain Research Seminar

Pittsburgh Center for Pain Research

Gating of Mechanosensitive Piezo and Swell Ion Channels in Droplet Lipid Bilayers

Rhuma Syeda

Scripps Research Institute

January 12, 2017 - 2:00pm

1495 BST

Syeda, R., M. N. Florendo, C. D. Cox, J. M. Kefauver, J. S. Santos, B. Martinac and A. Patapoutian (2016). "Piezo1 Channels Are Inherently Mechanosensitive." Cell Rep 17(7): 1739-1746.

Syeda, R.*, Z. Qiu*, A. E. Dubin, S. E. Murthy, M. N. Florendo, D. E. Mason, J. Mathur, S. M. Cahalan, E. C. Peters, M. Montal and A. Patapoutian (2016). "LRRC8 Proteins Form Volume-Regulated Anion Channels that Sense Ionic Strength." Cell 164(3): 499-511.